Melan-A/MART-1 Antibody (M2-7C10 + M2-9E3), PE/Cy5.5, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP234680PECY55

Catalog No. N234680PEC5

Description

Melan-A/MART-1 Monoclonal specifically detects Melan-A/MART-1 in Human, Mouse, Rat samples. It is validated for Flow Cytometry, Flow (Intracellular).

Specifications

• Antigen: Melan-A/MART-1
• Classification: Monoclonal
• Conjugate: PE-Cyanine5.5
• Formulation: PBS with 0.05% Sodium Azide
• Gene Symbols: MLANA
• Immunogen: Recombinant full-length hMelan-A/MART-1 protein (M2-7C10; M2-9E3) (Uniprot: Q16655)
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
• Content And Storage: Store at 4°C in the dark. Do not freeze.

• Applications: Flow Cytometry
• Clone: M2-7C10 + M2-9E3
• Dilution: Flow Cytometry, Flow (Intracellular)
• Gene Alias: Antigen LB39-AA, Antigen SK29-AA, Mart 1 Melan A, MART1MART-1, melan-A, melanoma antigen recognized by T-cells 1, Protein Melan-A
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Research Discipline: Cytoskeleton Markers, Immunology
• Gene ID (Entrez): 2315.0
• Target Species: Human, Mouse, Rat
• Isotype: IgG2b κ