Invitrogen™ Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M2)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA135616

Catalog No. 01-671-054

Description

This antibody stains a minority of primary melanomas and half of the metastatic lesions tested. It rarely stains dysplastic naevi or common cellular naevi using standard immunohistochemical conditions. The antibody recognizes two protein bands in immunoblotting with a molecular weight of 95-100 kD.

Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.

Specifications

• Antigen: Melanoma Discriminated Antigen
• Classification: Monoclonal
• Concentration: Conc. Not Determined
• Formulation: Tissue culture supernatant with 10mM sodium azide
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: 4°C
• Form: Liquid

• Applications: Immunohistochemistry (Frozen)
• Clone: PAL-M2
• Conjugate: Unconjugated
• Gene Alias: melanoma antigen; melanoma associated antigen
• Immunogen: Isolated from Human Melanoma cells.
• Regulatory Status: RUO
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1