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Invitrogen™ Melanoma Discriminated Antigen Monoclonal Antibody (PAL-M2)
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Catalog No. 01671054
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01-671-054 1 mL
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Catalog No. 01-671-054 Supplier Invitrogen™ Supplier No. MA135616
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Description

Mouse Monoclonal Antibody

This antibody stains a minority of primary melanomas and half of the metastatic lesions tested. It rarely stains dysplastic naevi or common cellular naevi using standard immunohistochemical conditions. The antibody recognizes two protein bands in immunoblotting with a molecular weight of 95-100 kD.

Melanoma is a malignant tumor of melanocytes which are found predominantly in skin but also in the bowel and the eye (see uveal melanoma). It is one of the rarer types of skin cancer but causes the majority of skin cancer related deaths. Despite many years of intensive laboratory and clinical research, the sole effective cure is surgical resection of the primary tumor before it achieves a thickness of greater than 1 mm.
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Specifications

Antigen Melanoma Discriminated Antigen
Applications Immunohistochemistry (Frozen)
Classification Monoclonal
Clone PAL-M2
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Tissue culture supernatant with 10mM sodium azide
Gene Alias melanoma antigen; melanoma associated antigen
Host Species Mouse
Immunogen Isolated from Human Melanoma cells.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG1
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