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Melanoma Marker (MART-1 + gp100) Antibody (DT101+ BC199 + HMB45), DyLight 594, Novus Biologicals™
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Catalog No. NB006231 Shop All R&D Systems Products
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NB006231 0.1 mL
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Catalog No. NB006231 Supplier Novus Biologicals Supplier No. NBP234608DL594
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Mouse Monoclonal Antibody

Melanoma Marker (MART-1 + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + gp100) in Human samples. It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin.

Specifications

Antigen Melanoma Marker (MART-1 + gp100)
Applications Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone DT101+ BC199 + HMB45
Conjugate DyLight 594
Dilution Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias MART1, MART-1
Host Species Mouse
Immunogen Recombinant hMART-1 protein (DT101& BC199); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Primary or Secondary Primary
Test Specificity This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ, IgG1 κ
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