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Melanoma Marker (MART-1 + Tyrosinase + gp100) Antibody (A103 + T311 + HMB45), Novus Biologicals™
SDP

Catalog No. p-7105589 Shop All R&D Systems Products
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0.02 mg
0.1 mg
0.2 mg
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Catalog No. Quantity
NBP234339F 0.02 mg
NBP234339A 0.1 mg
NBP234339B 0.2 mg
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Catalog No. NBP234339F Supplier Novus Biologicals Supplier No. NBP2343390.02MG
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Description

Mouse Monoclonal Antibody

Melanoma Marker (MART-1 + Tyrosinase + gp100) Monoclonal specifically detects Melanoma Marker (MART-1 + Tyrosinase + gp100) in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Flow (Intracellular).

Specifications

Antigen Melanoma Marker (MART-1 + Tyrosinase + gp100)
Applications Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Classification Monoclonal
Clone A103 + T311 + HMB45
Conjugate Unconjugated
Dilution Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Formulation PBS with 0.05% BSA. with 0.05% Sodium Azide
Gene Accession No. Q16655
Host Species Mouse
Immunogen Recombinant hMART-1 protein (A103); Recombinant tyrosinase protein (T311); Extract of pigmented melanoma metastases from lymph nodes (HMB45)
Purification Method Protein A purified
Quantity 0.02 mg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2315
Test Specificity This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. The function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1, IgG2a κ
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