Invitrogen™ Melanophilin Monoclonal Antibody (OTI6E8)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA527001

Catalog No. PIMA527001

Description

Melanophilin Monoclonal Antibody for Western Blot, IHC (P)

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.

Specifications

• Antigen: Melanophilin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BV36
• Gene Symbols: Mlph
• Immunogen: Human recombinant protein fragment corresponding to amino acids 295-600 of MLPH produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI6E8
• Conjugate: Unconjugated
• Gene: Mlph
• Gene Alias: 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; Exophilin-3; l(1)-3Rk; l1Rk3; leaden; leaden protein; Ln; Melanophilin; MGC2771; MGC59733; Mlph; OTTMUSP00000025451; SLAC2A; Slac-2a; SlaC2-a; Slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
• Host Species: Mouse
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79083
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid