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Invitrogen™ Melanophilin Polyclonal Antibody
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Catalog No. PIPA5100044
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100 μL
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PIPA5100044 100 μL
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Catalog No. PIPA5100044 Supplier Invitrogen™ Supplier No. PA5100044
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total Melanophilin.

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Melanophilin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Mlph
Gene Accession No. Q91V27, Q9BV36
Gene Alias 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; Exophilin-3; l(1)-3Rk; l1Rk3; leaden; leaden protein; Ln; Melanophilin; MGC2771; MGC59733; Mlph; OTTMUSP00000025451; SLAC2A; Slac-2a; SlaC2-a; Slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
Gene Symbols Mlph
Host Species Rabbit
Immunogen A synthesized peptide derived from human MLPH(Accession Q9BV36), corresponding to amino acid residues K539-H589.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171531, 316620, 79083
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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