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Invitrogen™ Melanophilin Polyclonal Antibody
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Catalog No. PIPA553212
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100 μL
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PIPA553212 100 μL
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Catalog No. PIPA553212 Supplier Invitrogen™ Supplier No. PA553212
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: ELTSNVSDQE TSSEEEEAKD EKAEPNRDKS VGPLPQADPE VSDIESRIAA LRAAGLTVKP SGKPRRKSNL PIFL Highest antigen sequence identity to the following orthologs: Mouse - 41%, Rat - 54%.

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Melanophilin
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mlph
Gene Accession No. Q9BV36
Gene Alias 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; Exophilin-3; l(1)-3Rk; l1Rk3; leaden; leaden protein; Ln; Melanophilin; MGC2771; MGC59733; Mlph; OTTMUSP00000025451; SLAC2A; Slac-2a; SlaC2-a; Slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
Gene Symbols Mlph
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human Melanophilin. Recombinant protein control fragment (Product #RP-90841).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 79083
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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