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Invitrogen™ Melanophilin Polyclonal Antibody
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Catalog No. PIPA597971
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100 μg
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Catalog No. Quantity
PIPA597971 100 μg
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Catalog No. PIPA597971 Supplier Invitrogen™ Supplier No. PA597971
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Description

Rabbit Polyclonal Antibody

Melanophilin Polyclonal Antibody for ELISA, ICC/IF, IHC (P), Western Blot

Slac2-a (for synaptotagmin-like protein (Slp) homolog lacking C2 domains-a) links Rab27A on melanosomes with Myosin VA in melanocytes. Slac2-a binds Myosin VA through a C-terminal region and GTP-bound Rab27A through its synaptotagmin-like protein homology domain (SHD), which is located near the N-terminus. The transport of pigment and cytotoxic granules in melanocytes requires the stable formation of this complex, and thus mutations in the binding domains of the three protein components may cause albinism and/or severe immune disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Melanophilin
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene Mlph
Gene Accession No. Q91V27, Q9BV36
Gene Alias 2210418F23Rik; 5031433I09Rik; AW228792; D1Wsu84e; Exophilin-3; l(1)-3Rk; l1Rk3; leaden; leaden protein; Ln; Melanophilin; MGC2771; MGC59733; Mlph; OTTMUSP00000025451; SLAC2A; Slac-2a; SlaC2-a; Slp homolog lacking C2 domains a; synaptotagmin-like protein 2a
Gene Symbols Mlph
Host Species Rabbit
Immunogen Recombinant Human Melanophilin protein (310-539AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 171531, 79083
Target Species Human, Mouse
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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