Melatonin, 99+%, PROMO, Thermo Scientific Chemicals

Description

Melatonine is a hormone usually produced in the pineal gland and released into the blood.

General Description

• Melatonine is a hormone produced by the pineal gland that shows several biological activities, including the somnolence, sleep-wake cycle, circadian rhythm, stress response, aging, and immunity activities
• It shows antioxidant, autocoid, paracoid, hormonal, anti- inflammatory and anti-apoptotic activities

Applications

• Melatonin shows neurohormonal activity and can upregulate antioxidant enzymes and inhibit rat NOS1
• Melatonin has been reported to be an activator of MEL-1A-R and MEL-1B-R
• The production and secretion of melatonine are dependent on beta-adrenergic receptor function
• During melatonine synthesis, the essential amino acid L-tryptophan is used as a precursor
• This compound inhibits apoptosis in immune cells and neurons, and enhances apoptotic cell death of cancer cells
• It can inhibit proliferation and metastasis of breast cancer cells by modulating Rho-associated kinase protein-1 expression

Specifications

Chemical Identifiers

• CAS: 73-31-4
• Molecular Formula: C13H16N2O2
• Molecular Weight (g/mol): 232.28 g/mol
• MDL Number: MFCD00005655
• InChI Key: DRLFMBDRBRZALE-UHFFFAOYSA-N
• Synonym: melatonin, melatonine, n-acetyl-5-methoxytryptamine, circadin, 5-methoxy-n-acetyltryptamine, n-2-5-methoxy-1h-indol-3-yl ethyl acetamide, melatol, melatonex, melovine
• PubChem CID: 896
• ChEBI: CHEBI:16796
• IUPAC Name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
• SMILES: CC(=O)NCCC1=CNC2=C1C=C(C=C2)OC

• Melting Point: 116°C to 120°C
• Color: White
• Quantity: 25 g
• Beilstein: 205542
• Merck Index: 14,5816
• Solubility Information: Soluble in ethanol
• Percent Purity: ≥99%
• Physical Form: Powder
• Chemical Name or Material: Melatonin

Safety and Handling

EINECSNumber	200-797-7
RTECSNumber	AC5955000
TSCA	No
Recommended Storage	Keep cold

RUO - Research Use Only