Membralin/C19orf6 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS11322R

Catalog No. 50-198-1267

Description

Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas.

Specifications

• Antigen: Membralin/C19orf6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMEM259
• Gene Alias: AC087114.7gm2; ASBABP1; aspecific BCL2 ARE-binding protein 1; C19orf6; C20H19orf6; im:7154960; MBRL; Membralin; mFLJ00277; ORF61; R32184_3; RGD1311136; Tmem259; Transmembrane protein 259
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 91304
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q4ZIN3
• Gene Symbols: TMEM259
• Immunogen: KLH conjugated synthetic peptide derived from human Membralin.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG