Invitrogen™ MEMO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5103089

Catalog No. PIPA5103089

Description

Antibody detects endogenous levels of total MEMO1.

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Specifications

• Antigen: MEMO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEMO1
• Gene Alias: 0610016J10Rik; C21orf19-like protein; C2orf4; CGI-27; D930048L02Rik; fi04d12; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; hypothetical protein LOC327360; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; MEMO1; Memo-1; Methylation modifier for class I HLA; NS5ATP7; protein memo; protein MEMO1; RGD1309929; Unknown (protein for MGC:127714); wu:fi04d12; zgc:55290
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51072, 7795
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9Y316
• Gene Symbols: MEMO1
• Immunogen: A synthesized peptide derived from human MEMO1(Accession Q9Y316), corresponding to amino acid residues M1-A44.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov