Invitrogen™ MEMO1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576423

Catalog No. PIPA576423

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Specifications

• Antigen: MEMO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEMO1
• Gene Alias: 0610016J10Rik; C21orf19-like protein; C2orf4; CGI-27; D930048L02Rik; fi04d12; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; hypothetical protein LOC327360; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; MEMO1; Memo-1; Methylation modifier for class I HLA; NS5ATP7; protein memo; protein MEMO1; RGD1309929; Unknown (protein for MGC:127714); wu:fi04d12; zgc:55290
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298787, 51072, 76890, 7795
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q4QQR9, Q91VH6, Q9Y316
• Gene Symbols: MEMO1
• Immunogen: Recombinant fusion protein of human MEMO1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG