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Invitrogen™ MEMO1 Polyclonal Antibody
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Catalog No. PIPA5114090
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100 μL
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PIPA5114090 100 μL
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Catalog No. PIPA5114090 Supplier Invitrogen™ Supplier No. PA5114090
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Rabbit Polyclonal Antibody

Immunogen sequence: AMESHKDEFT IIPVLVGALS ESKEQEFGKL FSKYLADPSN LFVVSSDFCH For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%.

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MEMO1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene MEMO1
Gene Accession No. Q9Y316
Gene Alias 0610016J10Rik; C21orf19-like protein; C2orf4; CGI-27; D930048L02Rik; fi04d12; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; hypothetical protein LOC327360; mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; MEMO; MEMO1; Memo-1; Methylation modifier for class I HLA; NS5ATP7; protein memo; protein MEMO1; RGD1309929; Unknown (protein for MGC:127714); wu:fi04d12; zgc:55290
Gene Symbols MEMO1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human MEMO1.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51072, 7795
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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