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MEMO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Catalog No. 501729577 Shop All Proteintech Group Inc Products
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50-172-9577 150 μL
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Catalog No. 50-172-9577 Supplier Proteintech Group Inc Supplier No. 146041AP150UL
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Description

Rabbit Polyclonal Antibody

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Specifications

Antigen MEMO1
Applications Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.19 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene MEMO1
Gene Accession No. Q4QQR9, Q91VH6, Q9Y316
Gene Alias C21orf19 like protein, C2orf4, CGI 27, mediator of cell motility 1, MEMO, Memo 1, MEMO1, NS5ATP7, Protein MEMO1
Gene Symbols MEMO1
Host Species Rabbit
Immunogen MEMO1 Fusion Protein Ag6151
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 298787, 51072, 76890
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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