MEMO1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 146041AP150UL

Catalog No. 50-172-9577

Description

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Specifications

• Antigen: MEMO1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MEMO1
• Gene Alias: C21orf19 like protein, C2orf4, CGI 27, mediator of cell motility 1, MEMO, Memo 1, MEMO1, NS5ATP7, Protein MEMO1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 298787, 51072, 76890
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Concentration: 0.19 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q4QQR9, Q91VH6, Q9Y316
• Gene Symbols: MEMO1
• Immunogen: MEMO1 Fusion Protein Ag6151
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG