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Invitrogen™ Menin Recombinant Rabbit Monoclonal Antibody (JE30-97)
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Catalog No. FEMA550803
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100 μL
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FEMA550803 100 μL
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Catalog No. FEMA550803 Supplier Invitrogen™ Supplier No. MA550803
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: 293 cell lysate, PC-3M cell lysate, Jurkat cell lysate, human lung cancer tissue, human testis tissue. Predicted band size: 68 kDa Subcellular Location: Nucleus.

Potassium channels are a group of ubiquitously expressed proteins that serve numerous functions in excitable and non-excitable cells. One class of integral membrane potassium channels is the large conductance, calcium-activated potassium channel (Maxi K+). Maxi K+ differs from most other potassium channels in that its activation is controlled by both increases in intracellular calcium and by membrane depolarization. Maxi K+ dual activation is possible because of its structure. The core of the channel, which is similar to other potassium channels, is a Maxi K+ alpha homotetramer that contains both a voltage sensor and an intracellular calcium binding domain. In vascular smooth muscle, an auxiliary beta-subunit is found in a 1:1 stoichiometry. The beta-subunit exhibits its effect on the Maxi K+ channel by effectively decreasing by 5- to 10- fold the concentration of calcium required to keep the pore open.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Menin
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE30-97
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene MEN1
Gene Accession No. O00255
Gene Alias AW045611; MEAI; MEN1; Menin; menin 1; multiple endocrine neoplasia 1; multiple endocrine neoplasia I; SCG2
Gene Symbols MEN1
Host Species Rabbit
Immunogen Synthetic peptide within Human Menin aa 566-615/615.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4221
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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