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Invitrogen™ MESDC2 Polyclonal Antibody
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Catalog No. PIPA5111140
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100 μL
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Catalog No. Quantity
PIPA5111140 100 μL
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Catalog No. PIPA5111140 Supplier Invitrogen™ Supplier No. PA5111140
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TPDESTPPPR KKKKDIRDYN DADMARLLEQ WEKDDDIEEG DLPEHKRPSA PVDFSKIDPS KPESILKMTK KGKTLMMFVT VSGSPT Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 88%.

MESDC2 chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4. May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MESDC2
Applications Western Blot
Classification Polyclonal
Concentration 0.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Mesd
Gene Accession No. Q14696
Gene Alias 2210015O11Rik; AW537813; BOCA; KIAA0081; LDLR chaperone MESD; LRP chaperone MESD; MESD; Mesdc2; MESDM; mesoderm development candiate 2; mesoderm development candidate 2; Mesoderm development LRP chaperone MESD; Mesoderm development protein; mKIAA0081; msd; renal carcinoma antigen NY-REN-61; UNQ1911/PRO4369
Gene Symbols Mesd
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human MESDC2. Recombinant protein control fragment (Product #RP-104741).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23184
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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