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MESDC2 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
SDP

Catalog No. 501726744 Shop All Proteintech Group Inc Products
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50-172-6744 150 μL
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Catalog No. 50-172-6744 Supplier Proteintech Group Inc Supplier No. 109581AP150UL
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Rabbit Polyclonal Antibody

MESDC2 chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction. Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (By similarity). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (By similarity).

Specifications

Antigen MESDC2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene MESD
Gene Accession No. Q14696, Q9ERE7
Gene Alias BOCA, KIAA0081, LDLR chaperone MESD, MESD, MESDC2, Mesoderm development protein
Gene Symbols Mesd
Host Species Rabbit
Immunogen MESDC2 Fusion Protein Ag1403
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23184, 67943
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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