Invitrogen™ METAP1 Monoclonal Antibody (248CT14.6.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA537522

Catalog No. PIMA537522

Description

METAP1 Monoclonal Antibody for Western Blot, IHC (P)

Methionine aminopeptidase 1 (METAP1) is a gene located on chromosome 4q24, encoding an enzyme responsible for the removal of N-terminal methionine residues from newly synthesized proteins. METAP1 is essential for protein maturation and function, as the cleavage of methionine allows subsequent modifications that are crucial for protein stability and activity. This enzyme is ubiquitously expressed in various tissues and plays a significant role in post-translational modification processes, affecting cellular homeostasis and protein regulation. METAP1 is involved in several physiological pathways, including cell cycle progression, signal transduction, and stress response. Dysregulation of METAP1 activity can impact protein function and is associated with diseases like cancer, reflecting its importance in cellular proliferation and growth. Research into METAP1 focuses on its potential as a therapeutic target for modulating protein synthesis and its implications in diseases characterized by uncontrolled cell growth.

Specifications

• Antigen: METAP1
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: P53582
• Gene Symbols: METAP1
• Immunogen: METAP1 recombinant protein.
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1 κ

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: 248CT14.6.1
• Conjugate: Unconjugated
• Gene: METAP1
• Gene Alias: 1700029C17Rik; AW047992; DKFZp781C0419; EC 3.4.11.18; fc84e12; im:7047238; KIAA0094; KIAA0094MAP 1; MAP 1; MAP1; MAP1A; metAP 1; Metap1; metap1 protein; MetAP1A; Methionine aminopeptidase 1; methionyl aminopeptidase 1; mKIAA0094; Peptidase M; Peptidase M 1; Putative methionine aminopeptidase 1 (MetAP 1) (Peptidase M 1); wu:fc84e12; zgc:110093
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 23173
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov