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Invitrogen™ METAP1 Monoclonal Antibody (248CT14.6.1)
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Catalog No. PIMA537522
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400 μL
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PIMA537522 400 μL
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Catalog No. PIMA537522 Supplier Invitrogen™ Supplier No. MA537522
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Description

Mouse Monoclonal Antibody

METAP1 Monoclonal Antibody for Western Blot, IHC (P)

Methionine aminopeptidase 1 (METAP1) is a gene located on chromosome 4q24, encoding an enzyme responsible for the removal of N-terminal methionine residues from newly synthesized proteins. METAP1 is essential for protein maturation and function, as the cleavage of methionine allows subsequent modifications that are crucial for protein stability and activity. This enzyme is ubiquitously expressed in various tissues and plays a significant role in post-translational modification processes, affecting cellular homeostasis and protein regulation. METAP1 is involved in several physiological pathways, including cell cycle progression, signal transduction, and stress response. Dysregulation of METAP1 activity can impact protein function and is associated with diseases like cancer, reflecting its importance in cellular proliferation and growth. Research into METAP1 focuses on its potential as a therapeutic target for modulating protein synthesis and its implications in diseases characterized by uncontrolled cell growth.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METAP1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 248CT14.6.1
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene METAP1
Gene Accession No. P53582
Gene Alias 1700029C17Rik; AW047992; DKFZp781C0419; EC 3.4.11.18; fc84e12; im:7047238; KIAA0094; KIAA0094MAP 1; MAP 1; MAP1; MAP1A; metAP 1; Metap1; metap1 protein; MetAP1A; Methionine aminopeptidase 1; methionyl aminopeptidase 1; mKIAA0094; Peptidase M; Peptidase M 1; Putative methionine aminopeptidase 1 (MetAP 1) (Peptidase M 1); wu:fc84e12; zgc:110093
Gene Symbols METAP1
Host Species Mouse
Immunogen METAP1 recombinant protein.
Purification Method Protein G
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23173
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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