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Invitrogen™ METAP1 Polyclonal Antibody
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Catalog No. PIPA547504
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100 μg
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PIPA547504 100 μg
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Catalog No. PIPA547504 Supplier Invitrogen™ Supplier No. PA547504
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Description

Goat Polyclonal Antibody

In Western blots, less than 1% cross-reactivity with recombinant mouse METAP1 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

Methionine aminopeptidase 1 (METAP1) is a gene located on chromosome 4q24, encoding an enzyme responsible for the removal of N-terminal methionine residues from newly synthesized proteins. METAP1 is essential for protein maturation and function, as the cleavage of methionine allows subsequent modifications that are crucial for protein stability and activity. This enzyme is ubiquitously expressed in various tissues and plays a significant role in post-translational modification processes, affecting cellular homeostasis and protein regulation. METAP1 is involved in several physiological pathways, including cell cycle progression, signal transduction, and stress response. Dysregulation of METAP1 activity can impact protein function and is associated with diseases like cancer, reflecting its importance in cellular proliferation and growth. Research into METAP1 focuses on its potential as a therapeutic target for modulating protein synthesis and its implications in diseases characterized by uncontrolled cell growth.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METAP1
Applications Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene METAP1
Gene Accession No. P53582
Gene Alias 1700029C17Rik; AW047992; DKFZp781C0419; EC 3.4.11.18; fc84e12; im:7047238; KIAA0094; KIAA0094MAP 1; MAP 1; MAP1; MAP1A; metAP 1; Metap1; metap1 protein; MetAP1A; Methionine aminopeptidase 1; methionyl aminopeptidase 1; mKIAA0094; Peptidase M; Peptidase M 1; Putative methionine aminopeptidase 1 (MetAP 1) (Peptidase M 1); wu:fc84e12; zgc:110093
Gene Symbols METAP1
Host Species Goat
Immunogen Sf 21-derived recombinant human Methionine Aminopeptidase1/METAP1 His52-Phe386.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23173
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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