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Invitrogen™ METAP1 Polyclonal Antibody
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Catalog No. PIPA558202
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100 μL
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PIPA558202 100 μL
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Catalog No. PIPA558202 Supplier Invitrogen™ Supplier No. PA558202
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: SVVRSYCGHG IHKLFHTAPN VPHYAKNKAV GVMKSGHVFT IEPMICEGGW QDETWPDGWT AVTRDGKRSA QFEH Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

Methionine aminopeptidase 1 (METAP1) is a gene located on chromosome 4q24, encoding an enzyme responsible for the removal of N-terminal methionine residues from newly synthesized proteins. METAP1 is essential for protein maturation and function, as the cleavage of methionine allows subsequent modifications that are crucial for protein stability and activity. This enzyme is ubiquitously expressed in various tissues and plays a significant role in post-translational modification processes, affecting cellular homeostasis and protein regulation. METAP1 is involved in several physiological pathways, including cell cycle progression, signal transduction, and stress response. Dysregulation of METAP1 activity can impact protein function and is associated with diseases like cancer, reflecting its importance in cellular proliferation and growth. Research into METAP1 focuses on its potential as a therapeutic target for modulating protein synthesis and its implications in diseases characterized by uncontrolled cell growth.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METAP1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene METAP1
Gene Accession No. P53582
Gene Alias 1700029C17Rik; AW047992; DKFZp781C0419; EC 3.4.11.18; fc84e12; im:7047238; KIAA0094; KIAA0094MAP 1; MAP 1; MAP1; MAP1A; metAP 1; Metap1; metap1 protein; MetAP1A; Methionine aminopeptidase 1; methionyl aminopeptidase 1; mKIAA0094; Peptidase M; Peptidase M 1; Putative methionine aminopeptidase 1 (MetAP 1) (Peptidase M 1); wu:fc84e12; zgc:110093
Gene Symbols METAP1
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human METAP1. Recombinant protein control fragment (Product #RP-102796).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23173
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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