Invitrogen™ Meteorin Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA562335

Catalog No. PIPA562335

Description

Immunogen sequence: VTHDVELQES VITVVAARVL RQTPPLFQAG RSGDQGLTSI RTPLRCGVHP GPGTFLFMGW SRFG Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.

Meteorin is a gene encoding a protein that is part of the cytokine and growth factor family, primarily involved in neurogenesis and gliogenesis. It is located on chromosome 17p13.1 and is highly expressed in the nervous system, where it plays a role in promoting the differentiation and maturation of astrocytes and neural precursor cells. Meteorin functions by enhancing neurite outgrowth and synaptic development, crucial for proper neural network formation. Additionally, it has been implicated in angiogenesis, contributing to the development and maintenance of blood vessels in neural tissue. Research suggests that Meteorin has neuroprotective properties and may help in recovery from neural injury, making it a molecule of interest for therapeutic strategies in neurodegenerative diseases and brain injuries. Its expression and activity are also being studied in relation to inflammatory responses and potential roles in other tissues, offering insights into its diverse biological functions beyond the central nervous system.

Specifications

• Antigen: Meteorin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: METRN
• Gene Alias: 1810034B16Rik; C16orf23; c380A1.2; hypoxia/reoxygenation regulatory factor; hypoxia/reoxygenation regulatory factor in astrocytes; Hyrac; Meteorin; meteorin, glial cell differentiation regulator; METRN; RGD1306222; RJD6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 79006
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UJH8
• Gene Symbols: METRN
• Immunogen: Recombinant protein corresponding to Human Meteorin. Recombinant protein control fragment (Product #RP-101168).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov