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Methicillin sodium salt, 90+%
Description
Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Methicillin Sodium Salt is inactivated by gastric acid so it is given to cells by other means in which gastric acid is not present in vitro.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP′s are enzymes which catalyze a pentagl

Specifications
Specifications
Type | Methicillin Sodium Salt |
Physical Form | Powder |
Melting Point | 196°C to 197°C (decomposition) |
Color | White |
Quantity | 1 g |
Flash Point | >110°C (230°F) |
Sensitivity | Light sensitive |
Boiling Point | 640°C |
Merck Index | 14,5969 |
Solubility Information | Slightly soluble in acetone; Soluble in ethanol or water |
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Safety and Handling
Hazard Category | H315-H317-H319-H334-H335 |
Hazard Statement | GHS H Statement H334-H335-H315-H319-H317 May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. |
Precautionary Statement | P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c |
EINECSNumber | 205-083-9 |
RTECSNumber | XH8950000 |
TSCA | No |
storageNote1 | -30° to -10°C |
Recommended Storage | Store at -20°C |
RUO – Research Use Only
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