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Methicillin sodium salt, 90+%

Catalog No. AAJ6641403
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Quantity:
1 g

CAS: 132-92-3 | C17H19N2NaO6S | 402.40 g/mol

Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP's are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Methicillin Sodium Salt is inactivated by gastric acid so it is given to cells by other means in which gastric acid is not present in vitro.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Targets primarily the cell wall of Gram-positive organisms especially Staphylococcus aureus. Methicillin is used to study bacterium susceptibility, and to inhibit cell-wall synthesis. PBP′s are enzymes which catalyze a pentagl
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 132-92-3
Molecular Formula C17H19N2NaO6S
Molecular Weight (g/mol) 402.40
MDL Number MFCD07787409
InChI Key MGFZNWDWOKASQZ-UMLIZJHQSA-M
Synonym Sodium (2,6-dimethoxyphenyl)penicillin; Sodium methicillin
PubChem CID 23667627
ChEBI CHEBI:52065
IUPAC Name sodium (2S,5R,6R)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
SMILES [Na+].COC1=CC=CC(OC)=C1C(=O)N[C@H]1[C@H]2SC(C)(C)[C@@H](N2C1=O)C([O-])=O

Specifications

Type Methicillin Sodium Salt
Physical Form Powder
Melting Point 196°C to 197°C (decomposition)
Color White
Quantity 1 g
Flash Point >110°C (230°F)
Sensitivity Light sensitive
Boiling Point 640°C
Merck Index 14,5969
Solubility Information Slightly soluble in acetone; Soluble in ethanol or water
Formula Weight 402.4
Percent Purity 98%
Chemical Name or Material Methicillin sodium salt
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Hazard Category H315-H317-H319-H334-H335
Hazard Statement GHS H Statement
H334-H335-H315-H319-H317
May cause allergy or asthma symptoms or breathing difficulties if inhaled.
May cause respiratory irritation.
Causes skin irritation.
Causes serious eye irritation.
May cause an allergic skin reaction.
Precautionary Statement P261-P264b-P271-P272-P280-P285-P302+P352-P304+P340-P305+P351+P338-P333+P313-P342+P311-P362-P501c
EINECSNumber 205-083-9
RTECSNumber XH8950000
TSCA No
storageNote1 -30° to -10°C
Recommended Storage Store at -20°C

RUO – Research Use Only

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