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Tocris Bioscience™ Methoxyluteolin

Catalog No. 732050
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Quantity:
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Inhibitor of pro-inflammatory mediator release from mast cells

Methoxyluteolin inhibits release of pro-inflammatory mediators from mast cells and decreases gene expression and release of TNF, VEGF and IL-8/CXCL8. The product also significantly inhibits IL-33 stimulated expression and release of CCL5 and CCL2. Methoxyluteolin pretreatment of LAD2 mast cells decreases gene expression of TNF, CXCL8 and VEGF in response to neurotensin or substance P via mTOR activation.

Specifications

Chemical Name or Material 2-(3,4-Dimethoxyphenyl)-5,7-dimethoxy-4 H-1-benzopyran-4-one
CAS 855-97-0
Quantity 50 mg
Target Cytokine Compounds
Molecular Formula C19H18O6
Purity 0.98
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