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Invitrogen™ METTL7A Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA520636
Description
A suggested positive control is MCF7 cell lysate. PA5-20636 can be used with blocking peptide PEP-0756.
MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
Specifications
METTL7A | |
Polyclonal | |
Unconjugated | |
METTL7A | |
2210414H16Rik; 3300001H21Rik; Aam-B; methyltransferase like 7A; methyltransferase like 7A1; methyltransferase like 7A-like; methyltransferase-like protein 7A; METTL7A; Mettl7a1; PRO0066; Protein AAM-B; RGD1308407; UbiE1; UNQ1902/PRO4348 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
25840, 70152 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Western Blot, Immunocytochemistry | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
Q9H8H3 | |
METTL7A, Mettl7a1 | |
A 13 amino acid peptide near the center of human MettL7A. | |
100 μg | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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