Invitrogen™ METTL7A Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA576353

Catalog No. PIPA576353

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Specifications

• Antigen: METTL7A
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: METTL7A
• Gene Alias: 2210414H16Rik; 3300001H21Rik; Aam-B; methyltransferase like 7A; methyltransferase like 7A1; methyltransferase like 7A-like; methyltransferase-like protein 7A; METTL7A; Mettl7a1; PRO0066; Protein AAM-B; RGD1308407; UbiE1; UNQ1902/PRO4348
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25840, 315306, 70152
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9H8H3
• Gene Symbols: METTL7A, Mettl7a1
• Immunogen: Recombinant fusion protein of human METTL7A.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG