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Invitrogen™ METTL7A Polyclonal Antibody
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Catalog No. PIPA596971
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100 μL
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PIPA596971 100 μL
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Catalog No. PIPA596971 Supplier Invitrogen™ Supplier No. PA596971
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: WICKKWFPYF LVRFTVIYNE QMASKKRELF SNLQEFAGPS GKLSLLEVGC GTGANFKFYP PGCRVTCIDP NPNFEKFLIK SIAENRHLQF ERFVVAAGEN MHQVADGSVD VVVCTLVLCS VKNQERILRE VCRVLRPGGA FYFMEHVAAE CSTWNYFWQQ VLDPAWHLLF DGCNLTRESW KALERASFSK LKLQHIQAPL SWELVRPHIY GYAVK; Positive Samples: 22Rv1; Cellular Location: Endoplasmic reticulum, Lipid droplet, Membrane.

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METTL7A
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1.49 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene METTL7A
Gene Accession No. Q9H8H3
Gene Alias 2210414H16Rik; 3300001H21Rik; Aam-B; methyltransferase like 7A; methyltransferase like 7A1; methyltransferase like 7A-like; methyltransferase-like protein 7A; METTL7A; Mettl7a1; PRO0066; Protein AAM-B; RGD1308407; UbiE1; UNQ1902/PRO4348
Gene Symbols METTL7A, Mettl7a1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 30-244 of human METTL7A (NP_0547523).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 25840, 315306, 70152
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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