Invitrogen™ METTL7B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520638

Catalog No. PIPA520638

Description

A suggested positive control is Jurkat cell lysate. PA5-20638 can be used with blocking peptide PEP-0758.

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Specifications

• Antigen: METTL7B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: METTL7B
• Gene Alias: 0610006F02Rik; AI266817; ALDI; associated with lipid droplet protein 1; associated with lipid droplets 1; methyltransferase like 7B; methyltransferase-like protein 7B; Mettl7b; RGD1305205; UNQ594/PRO1180
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 196410, 71664
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Immunohistochemistry, Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q6UX53, Q9DD20
• Gene Symbols: METTL7B
• Immunogen: A 13 amino acid peptide near the amino terminus of human MettL7B.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG