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Invitrogen™ METTL7B Polyclonal Antibody
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Catalog No. PIPA520638
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100 μg
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Catalog No. Quantity
PIPA520638 100 μg
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Catalog No. PIPA520638 Supplier Invitrogen™ Supplier No. PA520638
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20638 can be used with blocking peptide PEP-0758.

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen METTL7B
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene METTL7B
Gene Accession No. Q6UX53, Q9DD20
Gene Alias 0610006F02Rik; AI266817; ALDI; associated with lipid droplet protein 1; associated with lipid droplets 1; methyltransferase like 7B; methyltransferase-like protein 7B; Mettl7b; RGD1305205; UNQ594/PRO1180
Gene Symbols METTL7B
Host Species Rabbit
Immunogen A 13 amino acid peptide near the amino terminus of human MettL7B.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 196410, 71664
Target Species Human, Mouse
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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