Invitrogen™ METTL7B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5121075

Catalog No. PIPA5121075

Description

Positive test controls include: HT-29, Mouse liver, Rat liver. Immunogen sequence: RPGGVLFFWE HVAEPYGSWA FMWQQVFEPT WKHIGDGCCL TRETWKDLEN AQFSEIQMER QPPPLKWLPV GPHIMGKAVK.

MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

Specifications

• Antigen: METTL7B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: METTL7B
• Gene Alias: 0610006F02Rik; AI266817; ALDI; associated with lipid droplet protein 1; associated with lipid droplets 1; methyltransferase like 7B; methyltransferase-like protein 7B; Mettl7b; RGD1305205; UNQ594/PRO1180
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 196410, 366792, 71664
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 1.544 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: Q562C4, Q6UX53, Q9DD20
• Gene Symbols: METTL7B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 165-244 of human METTL7B (NP_689850.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG