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MFN1 Monoclonal Antibody (OTI3C5), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA802216

Encompass_Preferred

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Catalog No. 50-167-9154


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Description

Description

MFN1 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
Specifications

Specifications

MFN1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Q8IWA4
MFN1
Human recombit protein fragment corresponding to amino acids 209-469 of human MFN1 produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI3C5
Unconjugated
MFN1
hfzo1, hfzo2
Mouse
Affinity Chromatography
RUO
55669
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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