Learn More
MFN1 Mouse anti-Human, Clone: OTI4H4, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF802150

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
MFN1 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.Specifications
MFN1 | |
Monoclonal | |
Unconjugated | |
MFN1 | |
hfzo1, hfzo2 | |
Mouse | |
Affinity Chromatography | |
RUO | |
55669 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
OTI4H4 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
Q8IWA4 | |
MFN1 | |
Human recombit protein fragment corresponding to amino acids 209-469 of human MFN1 produced in E.coli. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG1 |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.