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Invitrogen™ MFN1 Polyclonal Antibody
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Catalog No. PIPA5142310
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100 μg
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Catalog No. Quantity
PIPA5142310 100 μg
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Catalog No. PIPA5142310 Supplier Invitrogen™ Supplier No. PA5142310
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Description

Goat Polyclonal Antibody

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MFN1
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene MFN1
Gene Accession No. Q8IWA4
Gene Alias 2310002F04Rik; 6330416C07Rik; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; Mfn1; MFN2; MGC41806; mitochondrial mitofusin 1; mitochondrial transmembrane GTPase Fzo-1; mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; mitofusin-1; mKIAA4032; putative transmembrane GTPase; transmembrane GTPase MFN1
Gene Symbols MFN1
Host Species Goat
Immunogen Peptide with sequence C-NKAVQLENELEN (aa 717-728).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55669
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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