Mfn1 Rabbit anti-Human, Polyclonal, Bioss

Rabbit Polyclonal Antibody

Supplier:  Bioss BS0557R

Catalog No. 50-198-0351

Description

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Specifications

• Antigen: Mfn1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFN1
• Gene Alias: 2310002F04Rik; 6330416C07Rik; BOS_1047; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; LOC100346474; Mfn1; MFN2; MGC41806; mitochondrial transmembrane GTPase Fzo-1; Mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; Mitofusin-1; mKIAA4032; putative transmembrane GTPase; Transmembrane GTPase MFN1
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 55669
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 μg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene Accession No.: Q8IWA4
• Gene Symbols: MFN1
• Immunogen: KLH conjugated synthetic peptide derived from human Mfn 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG