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Mfn1 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501980351
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100 μL
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Catalog No. Quantity
50-198-0351 100 μL
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Catalog No. 50-198-0351 Supplier Bioss Supplier No. BS0557R
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Description

Rabbit Polyclonal Antibody

Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development. When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane.

Specifications

Antigen Mfn1
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene MFN1
Gene Accession No. Q8IWA4
Gene Alias 2310002F04Rik; 6330416C07Rik; BOS_1047; D3Ertd265e; DKFZp762F247; EC 3.6.5; FLJ20693; Fzo homolog; Fzo1b; hfzo1; hfzo2; HR2; LOC100346474; Mfn1; MFN2; MGC41806; mitochondrial transmembrane GTPase Fzo-1; Mitochondrial transmembrane GTPase FZO1B; mitochondrial transmembrane GTPase FZO-2; mitofusin 1; mitofusin 2; Mitofusin-1; mKIAA4032; putative transmembrane GTPase; Transmembrane GTPase MFN1
Gene Symbols MFN1
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human Mfn 1.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55669
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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