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Invitrogen™ MFN2 Polyclonal Antibody
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Catalog No. PIPA589321
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100 μL
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PIPA589321 100 μL
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Catalog No. PIPA589321 Supplier Invitrogen™ Supplier No. PA589321
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Rabbit Polyclonal Antibody

Positive Samples: Mouse brain, Rat brain; Cellular Location: Mitochondrion outer membrane, Multi-pass membrane protein Immunogen sequence: TTEEQVLDVK GYLSKVRGIS EVLARRHMKV AFFGRTSNGK STVINAMLWD KVLPSGIGHT TNCFLRVGGT DGHEAFLLTE GSEEKKSVKT VNQLAHALHQ DEQLHAGSMV SVMWPNSKCP LLKDDLVLMD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKQ FFHKVSERLS RPNIFILNNR W.

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MFN2
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1.38 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene MFN2
Gene Accession No. O95140, Q80U63, Q8R500
Gene Alias CMT2A; CMT2A2; CPRP 1; CPRP1; D630023P19Rik; Fzo; HMSN6A; HSG; HSG protein; hyperplasia suppressor; hypertension related protein 1; hypertension-related protein; hypertension-related protein 1; Kiaa0214; LOW QUALITY PROTEIN: mitofusin-2; Marf; MFN 2; MFN2; mg:cb01g09; Mitochondrial assembly regulatory factor; mitochondrial transmembrane GTPase FZO1A; mitofusin 2; Mitofusin2; mitofusin-2; si:dkeyp-104h9.2; Transmembrane GTPase MFN2; wu:fb79a11
Gene Symbols MFN2
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of mouse Mitofusin 2 (NP_5734642).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 170731, 64476, 9927
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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