Invitrogen™ MFN2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589321

Catalog No. PIPA589321

Description

Positive Samples: Mouse brain, Rat brain; Cellular Location: Mitochondrion outer membrane, Multi-pass membrane protein Immunogen sequence: TTEEQVLDVK GYLSKVRGIS EVLARRHMKV AFFGRTSNGK STVINAMLWD KVLPSGIGHT TNCFLRVGGT DGHEAFLLTE GSEEKKSVKT VNQLAHALHQ DEQLHAGSMV SVMWPNSKCP LLKDDLVLMD SPGIDVTTEL DSWIDKFCLD ADVFVLVANS ESTLMQTEKQ FFHKVSERLS RPNIFILNNR W.

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Specifications

• Antigen: MFN2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFN2
• Gene Alias: CMT2A; CMT2A2; CPRP 1; CPRP1; D630023P19Rik; Fzo; HMSN6A; HSG; HSG protein; hyperplasia suppressor; hypertension related protein 1; hypertension-related protein; hypertension-related protein 1; Kiaa0214; LOW QUALITY PROTEIN: mitofusin-2; Marf; MFN 2; MFN2; mg:cb01g09; Mitochondrial assembly regulatory factor; mitochondrial transmembrane GTPase FZO1A; mitofusin 2; Mitofusin2; mitofusin-2; si:dkeyp-104h9.2; Transmembrane GTPase MFN2; wu:fb79a11
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170731, 64476, 9927
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.38 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
• Gene Accession No.: O95140, Q80U63, Q8R500
• Gene Symbols: MFN2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 70-260 of mouse Mitofusin 2 (NP_5734642).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG