Invitrogen™ MFN2 Recombinant Rabbit Monoclonal Antibody (7H42L13)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ 702768

Catalog No. 70-276-8

Description

This antibody is predicted to react with Monkey, Dog, Cat, Bovine. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

This gene encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. This protein is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Specifications

• Antigen: MFN2
• Classification: Recombinant Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: O95140, Q80U63
• Gene Symbols: MFN2
• Immunogen: Peptides corresponding to human Mitofusin 2 [1) aa391-aa410 2) aa742-aa757].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Western Blot
• Clone: 7H42L13
• Conjugate: Unconjugated
• Gene: MFN2
• Gene Alias: CMT2A; CMT2A2; CPRP 1; CPRP1; D630023P19Rik; Fzo; HMSN6A; HSG; HSG protein; hyperplasia suppressor; hypertension related protein 1; hypertension-related protein; hypertension-related protein 1; Kiaa0214; LOW QUALITY PROTEIN: mitofusin-2; Marf; MFN 2; MFN2; mg:cb01g09; Mitochondrial assembly regulatory factor; mitochondrial transmembrane GTPase FZO1A; mitofusin 2; Mitofusin2; mitofusin-2; si:dkeyp-104h9.2; Transmembrane GTPase MFN2; wu:fb79a11
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 170731, 9927
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov