Invitrogen™ MFNG Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142901

Catalog No. PIPA5142901

Description

Additional Information: This antibody is expected to recognize isoform 1 (NP_002396.2). This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.

This gene is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Specifications

• Antigen: MFNG
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFNG
• Gene Alias: AW546563; beta-1,3-N-acetylglucosaminyltransferase manic fringe; EC 2.4.1.222; manic fringe homolog; Mfng; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 4242
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O00587
• Gene Symbols: MFNG
• Immunogen: Peptide with sequence C-NRPIHASEPQPHNRT.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG