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Invitrogen™ MFSD2A Polyclonal Antibody
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Catalog No. PIPA560242
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PIPA560242 100 μL
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Catalog No. PIPA560242 Supplier Invitrogen™ Supplier No. PA560242
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: IVGQADTPCF QDLNSSTVAS QSANHTHGTT SHRETQ Highest antigen sequence identity to the following orthologs: Mouse - 56%, Rat - 58%.

Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MFSD2A
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.10 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene MFSD2A
Gene Accession No. Q8NA29
Gene Alias 1700018O18Rik; HMFN0656; major facilitator superfamily domain containing 2; major facilitator superfamily domain containing 2A; major facilitator superfamily domain-containing protein 2A; MCPH15; MFSD2; MFSD2A; NLS1; PP9177; RGD1310174; sodium-dependent LPC symporter 1; sodium-dependent lysophosphatidylcholine symporter 1; UNQ300/PRO341; zgc:101615
Gene Symbols MFSD2A
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human MFSD2A. Recombinant protein control fragment (Product #RP-99818).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84879
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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