Invitrogen™ MFSD2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA560628

Catalog No. PIPA560628

Description

Immunogen sequence: VGSTPKTPSR DASSRLSLRR RTSYSL Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 85%.

Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.

Specifications

• Antigen: MFSD2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MFSD2B
• Gene Alias: hMfsd2b; major facilitator superfamily domain containing 2B; major facilitator superfamily domain-containing protein 2B; MFSD2B; RGD1561716
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 388931
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: A6NFX1
• Gene Symbols: MFSD2B
• Immunogen: Recombinant protein corresponding to Human MFSD2B. Recombinant protein control fragment (Product #RP-99710).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG