Invitrogen™ MGA Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA559934

Catalog No. PIPA559934

Description

Immunogen sequence: KLGDVKVEQQ KGFDNPEENS SEFPVTFKEE SKFELSGSKV MEQQSNLQPE AKEKECGDSL EKDRERWRKH LKGPLTRKCV GASQECKKEA DEQLIKETKT CQENSDVFQQ EQGISDLLGK SGITEDARVL KTECDSWSRI S Highest antigen sequence identity to the following orthologs: Mouse - 61%, Rat - 62%.

Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. [UniProt].

Specifications

• Antigen: MGA
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MGA
• Gene Alias: AV312082; C130042M01Rik; C80739; D030062C11Rik; FLJ12634; KIAA0518; Kiaa4252; LOW QUALITY PROTEIN: MAX gene-associated protein; Mad5; maltase-glucoamylase (alpha-glucosidase); Max dimerization protein 5; MAX dimerization protein MGA; MAX gene associated; MAX gene-associated protein; MAX protein-associated protein-like protein; MAX-associated protein; MAX-interacting protein; MGA; MGA, MAX dimerization protein; MGA-like protein; MXD5; RGD1561597
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23269
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q8IWI9
• Gene Symbols: MGA
• Immunogen: Recombinant protein corresponding to Human MGA. Recombinant protein control fragment (Product #RP-102486).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG