Invitrogen™ MGAT2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA597186

Catalog No. PIPA597186

Description

Immunogen sequence: PFSIQLYPNE FPGSDPRDCP RDLPKNAALK LGCINAEYPD SFGHYREAKF SQTKHHWWWK LHFVWERVKI LRDYAGLILF LEEDHYLAPD FYHVFKKMWK LKQQECPECD VLSLGTYSAS RSFYGMADKV DVKTWKSTEH NMGLALTRNA YQKLIECTDT FCTYDDYNWD WTLQYLTVSC LPKFWKVLVP QIPRIFHAGD CGMHHKKTCR PSTQSAQIES LLNNNKQYMF PETLTISEKF TVVAISPPRK NGGWGDIRDH ELCKSYRRLQ; Positive Samples: K-562, Mouse kidney, Rat kidney; Cellular Location: Golgi apparatus membrane, Single-pass type II membrane protein.

The product of this gene is a Golgi enzyme catalyzing an essential step in the conversion of oligomannose to complex N-glycans. The enzyme has the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain, and a C-terminal catalytic domain. Mutations in this gene may lead to carbohydrate-deficient glycoprotein syndrome, type II. The coding region of this gene is intronless. Transcript variants with a spliced 5' UTR may exist, but their biological validity has not been determined.

Specifications

• Antigen: MGAT2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MGAT2
• Gene Alias: AA407964; alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase; Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase-like protein; beta-1,2-N-acetylglucosaminyltransferase II; beta-12-N-acetylglucosaminyltransferase II; CDG2A; CDGS2; CH73-301C19.1; GlcNAc-T II; GLCNACTII; GNT2; GNT-II; Mannoside acetylglucosaminyltransferase 2; mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase; mgat2; N-glycosyl-oligosaccharide-glycoprotein N-acetylglucosaminyltransferase II; UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II; zgc:162268
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 217664, 4247, 94273
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.45 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q09326, Q10469, Q921V5
• Gene Symbols: MGAT2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 178-447 of human MGAT2 (NP_0023991).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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