Invitrogen™ MGAT5B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100612

Catalog No. PIPA5100612

Description

Antibody detects endogenous levels of total MGAT5B.

Glycosyltransferase that acts on alpha-linked mannose of N-glycans and O-mannosyl glycans. Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAcbeta1,2-Manalpha on both the alpha1,3- and alpha1,6-linked mannose arms in the core structure of N-glycan. Also acts on the GlcNAcbeta1,2-Manalpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adhesion and migration of neuronal cells via its activity in the O-mannosyl glycan pathway.

Specifications

• Antigen: MGAT5B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: MGAT5B
• Gene Alias: Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase B; beta(1,6)-N-acetylglucosaminyltransferase V; beta1,6-N-acetylglucosaminyltransferase IX (GnT-IX); C330018B01; GlcNAc-T Vb; GnT-IX; GNT-Vb; hGnTVb; KIAA2008; mannoside acetylglucosaminyltransferase 5, isoenzyme B; mannoside acetylglucosaminyltransferase 5B; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isoenzyme B; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B; Mgat5b; mGnTVB; N-acetylglucosaminyltranferase VB; N-acetylglucosaminyltransferase IX; N-acetylglucosaminyl-transferase Vb; UDP-N-acetylglucosamine: alpha1,6-D-mannoside beta1,6-N-acetylglucosaminyltransferase b
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 146664, 268510, 303693
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q3V5L5, Q765H6
• Gene Symbols: MGAT5B
• Immunogen: A synthesized peptide derived from human MGAT5B(Accession Q3V5L5), corresponding to amino acid residues D136-A186.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov