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Invitrogen™ mGluR2/mGluR3 Polyclonal Antibody
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Catalog No. PIPA146113
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100 μg
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Catalog No. Quantity
PIPA146113 100 μg
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Catalog No. PIPA146113 Supplier Invitrogen™ Supplier No. PA146113
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Description

Rabbit Polyclonal Antibody

This antibody is predicted react to human and mouse based on sequence homology.

The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR2/mGluR3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene Grm2
Gene Accession No. P31421, P31422
Gene Alias 0710001G23Rik; 4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member C; GLUR2; GLUR3; glutamate metabotropic receptor 2; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; glutamate receptor, metabotropic 3; Gprc1b; GPRC1C; GRM2; Grm3; M mGlu3; Metabotropic glutamate receptor 2; metabotropic glutamate receptor 3; mGlu2; mGlu3; mGluR2; MGLUR3; mGluR7
Gene Symbols Grm2, Grm3
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues 860-875 of the rat mGlurR2/3 protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24415, 24416
Target Species Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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