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Invitrogen™ mGluR2/mGluR3 Polyclonal Antibody
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Catalog No. PIPA599168
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PIPA599168 100 μL
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Catalog No. PIPA599168 Supplier Invitrogen™ Supplier No. PA599168
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total mGluR2/3.

The mGluR proteins (metabotropic Glutamate Receptors) are members of the G-protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G-proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G-protein that inhibits adenylate cyclase activity. mGluR-3, which may interact with GRASP, acts as a receptor for glutamate.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR2/mGluR3
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Grm2
Gene Accession No. P31421, P31422, Q14416, Q14832, Q14BI2, Q9QYS2
Gene Alias 0710001G23Rik; 4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member C; GLUR2; GLUR3; glutamate metabotropic receptor 2; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; glutamate receptor, metabotropic 3; Gprc1b; GPRC1C; GRM2; Grm3; M mGlu3; Metabotropic glutamate receptor 2; metabotropic glutamate receptor 3; mGlu2; mGlu3; mGluR2; MGLUR3; mGluR7
Gene Symbols Grm2, Grm3
Host Species Rabbit
Immunogen A synthesized peptide derived from human GRM2(Accession Q14416), corresponding to amino acid residues I687-L737.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108068, 108069, 24415, 24416, 2912, 2913
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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