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mGluR2 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA123573
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25 μg
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Catalog No. Quantity
PIPA123573 25 μg
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Catalog No. PIPA123573 Supplier Thermo Scientific Supplier No. PA123573

Description

Rabbit Polyclonal Antibody

PA1-23573 detects Metabotropic Glutamate Receptor 2 in Human samples.

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide
Gene GRM2
Gene Accession No. Q14416
Gene Alias 4930441L02Rik; G protein coupled receptor, family C, group 1, member B; G protein-coupled receptor, family C, group 1, member B; GLUR2; glutamate metabotropic receptor 2; glutamate receptor; glutamate receptor homolog; glutamate receptor, metabotropic 2; GPRC1B; Grm2; M mGlu2; Metabotropic; Metabotropic glutamate receptor 2; mGlu2; MGLUR2; mGluR7
Gene Symbols GRM2
Host Species Rabbit
Immunogen Synthetic 18 amino acid peptide from N-terminal extracellular domain of human mGluR2
Purification Method Antigen affinity chromatography
Quantity 25 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2912
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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