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mGluR3 Polyclonal Antibody, Invitrogen™

Catalog No. PIPA129424
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Quantity:
100 μL
Catalog No. Quantity
PIPA129424 100 μL
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Catalog No. PIPA129424

Supplier: Thermo Scientific PA129424

Description

Rabbit Polyclonal Antibody

Recommended positive controls: Rat Cerebellar and cortical Membrane.

Glutamate is the main excitatory neurotransmitter in the brain. For many years it had been considered to act only on the ligand-gated receptor channels-termed NMDA, AMPA and kainite receptors that are involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate enzymes producing second messengers via specific receptors coupled to G-proteins. These receptors are called metabotropic glutamate receptors. In expression systems, Group-I receptors stimulate phospholipase C as revealed by an increase in phosphoinositide turnover and calcium release from internal stores. Group-II and -III receptors are coupled to the inhibition of adenylyl cyclase. The Group-I receptors include mGluR1a and mGluR5. The Group-II receptors in include mGluR2 and mGluR3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR3
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation tris glycine with 1% BSA and 0.1% sodium azide; pH 7.8
Gene GRM3
Gene Accession No. P31422, Q14832, Q9QYS2
Gene Alias 0710001G23Rik; G protein-coupled receptor, family C, group 1, member C; GLUR3; glutamate metabotropic receptor 3; glutamate receptor; glutamate receptor, metabotropic 3; Gprc1c; GRM3; M mGlu3; Metabotropic glutamate receptor 3; mGlu3; mGluR3
Gene Symbols GRM3
Host Species Rabbit
Immunogen synthetic peptide TKVDEAEYM, corresponding to amino acids 118-126 of Rat metabotropic Glutamate Receptor 3.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108069, 24416, 2913
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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