Invitrogen™ mGluR4 Polyclonal Antibody

Catalog No.	Quantity
PIPA5118599	100 μL

Catalog No. PIPA5118599 Supplier Invitrogen™ Supplier No. PA5118599

Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total mGluR4.

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: mGluR4
• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene: GRM4
• Gene Accession No.: P31423, Q14833, Q68EF4
• Gene Alias: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; glutamate metabotropic receptor 4; glutamate receptor; glutamate receptor, metabotropic 4; GPRC1D; GRM4; Metabotropic glutamate receptor 4; mGlu4; MGLUR4
• Gene Symbols: GRM4
• Host Species: Rabbit
• Immunogen: A synthesized peptide derived from human GRM4(Accession Q14833), corresponding to amino acid residues R856-T906.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24417, 268934, 2914
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG