Invitrogen™ mGluR4 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5118599

Catalog No. PIPA5118599

Description

Antibody detects endogenous levels of total mGluR4.

The Metabotropic Glutamate Receptor mGluR4/GRM4 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties.

Specifications

• Antigen: mGluR4
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRM4
• Gene Alias: G protein-coupled receptor GRM4; G protein-coupled receptor, family C, group 1, member D; glutamate metabotropic receptor 4; glutamate receptor; glutamate receptor, metabotropic 4; GPRC1D; GRM4; Metabotropic glutamate receptor 4; mGlu4; MGLUR4
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 24417, 268934, 2914
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P31423, Q14833, Q68EF4
• Gene Symbols: GRM4
• Immunogen: A synthesized peptide derived from human GRM4(Accession Q14833), corresponding to amino acid residues R856-T906.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG