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Invitrogen™ mGluR5 Recombinant Rabbit Monoclonal Antibody (4I1G3)
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Catalog No. PIMA538097
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100 μL
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PIMA538097 100 μL
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Catalog No. PIMA538097 Supplier Invitrogen™ Supplier No. MA538097
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Description

Rabbit Recombinant Monoclonal Antibody

Positive Samples: Mouse brain Immunogen sequence: PKEIQLPTTM TTFAEIQPLP AIEVTGGAQP AAGAQAAGDA ARESPAAGPE AAAAKPDLEE LVALTPPSPF RDSVDSGSTT PNSPVSESAL CIPSSPKYDT L.

GRK1 is a member of the guanine nucleotide protein-coupled (G protein) receptor kinase subfamily of Serine/Threonine kinase family. GRK1 phosphorylates rhodopsin and initiates its deactivation. G protein mediated phosphorylation promotes the binding of arrestin, which removes the receptor from the G-protein and terminates the receptor signal chain. GRK1 is farnesylated to promote membrane association. Studies have shown that GRK1 has been shown to be inhibited by recoverin, a Calcium binding protein. Diseases associated with GRK1 protein dysfunction include Oguchi Disease-2 and Hereditary Night Blindness.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR5
Applications ELISA, Western Blot
Classification Recombinant Monoclonal
Clone 4I1G3
Concentration 0.6 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Grm5
Gene Accession No. P31424, Q3UVX5
Gene Alias 6430542K11Rik; A830007B11Rik; AI850523; D16Ium24; D16Ium24e; G protein coupled receptor, family C, group 1, member E; G protein-coupled receptor GRM5; G protein-coupled receptor, family C, group 1, member E; Glu5R; Glur5; Glur-5; Glurbeta1; glutamate metabotropic receptor 5; glutamate receptor; glutamate receptor, metabotropic 5; GPRC1A; GPRC1E; GRM 1; GRM 5; GRM1; GRM1 alpha; GRM1A; Grm5; metabotropic 1; metabotropic glutamate receptor (mGluR5); metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor subtype 5b; metabotropic glutamate receptor type 5; MGC25101; mGlu1; mGlu5; mGluR; mGluR1; mGluR1 alpha; mGluR1A; MGLUR5; mGluR5a; mGluR5b; PPP1R86; protein phosphatase 1, regulatory subunit 86
Gene Symbols Grm5
Host Species Rabbit
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1100-1200 of human GRM5 (P41594).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 108071, 24418
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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