Invitrogen™ mGluR6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA532862

Catalog No. PIPA532862

Description

Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Marmoset (100%); Rat, Dog, Panda, Rabbit (83%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors. Ionotropic glutamate receptors are oligomeric complexes of various subunits (GluR17, NMDA13, KAI2), which comprise ligand-gated calcium channels. Metabotropic glutamate receptors are G-protein coupled receptors, which when activated can activate phopholipases or adenylylcyclase, depending on the neuron.

Specifications

• Antigen: mGluR6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRM6
• Gene Alias: BC021919; CSNB1B; G protein-coupled receptor GRM6; G protein-coupled receptor, family C, group 1, member F; glutamate metabotropic receptor 6; glutamate receptor; glutamate receptor, metabotropic 6; Gm3; GPRC1F; Grm6; Metabotropic glutamate receptor 6; mGlu6; MGLUR6; nerg1; nob2; nob3; nob4
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2916
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: O15303
• Gene Symbols: GRM6
• Immunogen: Synthetic 12 amino acid peptide from N-terminal extracellular domain of human GRM6 / MGLUR6.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human, Monkey
• Product Type: Antibody
• Isotype: IgG