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Invitrogen™ mGluR8 Monoclonal Antibody (4C1C1)
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Catalog No. PIMA531755
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100 μL
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Catalog No. Quantity
PIMA531755 100 μL
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Catalog No. PIMA531755 Supplier Invitrogen™ Supplier No. MA531755
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Description

Mouse Monoclonal Antibody

MA5-31755 has been tested in indirect ELISA.

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
TRUSTED_SUSTAINABILITY

Specifications

Antigen mGluR8
Applications ELISA, Flow Cytometry, Western Blot
Classification Monoclonal
Clone 4C1C1
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene GRM8
Gene Accession No. O00222
Gene Alias A230002O04; FLJ41058; G protein coupled receptor, family C, group 1, member H; G protein-coupled receptor family C group 1 member H; G protein-coupled receptor, family C, group 1, member H; GLUR8; glutamate metabotropic receptor 8; glutamate receptor; glutamate receptor, metabotropic 8; Gprc1h; Grm8; M mGlu8; Metabotropic glutamate receptor 8; metabotropic glutamate receptor subtype 8b; MGC126724; mGlu8; mGlur; mGluR8; mGluR8b
Gene Symbols GRM8
Host Species Mouse
Immunogen Purified recombinant fragment of human GRM8 (AA: extra 440-583) expressed in E. coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2918
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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