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MGMT Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
$156.65 - $620.58
Specifications
| Antigen | MGMT |
|---|---|
| Concentration | Lot-Specific |
| Applications | Immunoprecipitation, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-2994
|
Active Motif
39952 |
10 μL |
Each for $156.65
|
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50-199-2993
|
Active Motif
39951 |
100 μL |
Each for $620.58
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Description
O6-Methylguanine-DNA Methyltransferase (MGMT) is an important DNA repair protein involved in tumor cell resistance to the cytostatic activity of chemotherapeutic alkylating agents. This protein is also effective in protecting normal cells against the genotoxic and carcinogenic effects of DNA alkylation. The alkylating drug resistance is caused by MGMT's ability to remove DNA alkyl groups introduced in the O6 position of guanine. MGMT is expressed in highly variable amounts, depending upon the cell and tissue type, species, and cellular growth characteristics. In addition, MGMT activity varies among groups of tumors and within a particular type of tumor.Specifications
| MGMT | |
| Immunoprecipitation, Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P16455 | |
| 4255 | |
| This MGMT antibody was raised against a peptide derived from the C-terminal region of human MGMT. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| MGMT |
| Lot-Specific | |
| Polyclonal | |
| Liquid | |
| RUO | |
| 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8 | |
| 0-6-methylguanine-DNA methyltransferase; 6-O-methylguanine-DNA methyltransferase; Agat; AGT; AI267024; methylated DNA protein cysteine methyltransferase; Methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; MGMT; O(6)-alkylguanine-DNA alkyltransferase; O-6-alkylguanine-DNA alkyltransferase; O6-alkylguanine-DNA alkyltransferase; O-6-methylguan; O6-methylguanine-DNA methyltranferase; O-6-methylguanine-DNA methyltransferase; O6-methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase | |
| MGMT | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
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