Invitrogen™ RT1.Ac Monoclonal Antibody (OX-27), PE

Catalog No.	Quantity
PIMA528195	100 Tests

Catalog No. PIMA528195

Supplier: Invitrogen™ MA528195

Description

Mouse Monoclonal Antibody

This antibody recognizes a polymorphic determinant (c haplotype) of rat Class I MHC Antigen (RT-1A). Reconstitute by adding 1 mL distilled water.

RT1.Ac is a gene located within the major histocompatibility complex (MHC) region of the rat genome and is a part of the class I MHC genes. The MHC genes are involved in the immune response by presenting peptide antigens to T cells, enabling the immune system to recognize and respond to pathogens. RT1.Ac encodes for a protein that is a homolog to human HLA and mouse H2 class I molecules, playing a crucial role in the activation and regulation of immune responses. This gene's expression on the surface of cells allows for the presentation of endogenous peptides to cytotoxic T lymphocytes, facilitating the detection and destruction of infected or malignantly transformed cells. Researchers often use RT1.Ac in studies involving transplantation immunology and autoimmune disease models, due to its pivotal role in antigen presentation and immune recognition.

Specifications

• Antigen: RT1.Ac
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: OX-27
• Concentration: Conc. Not Determined
• Conjugate: PE
• Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
• Gene: RT1-A1
• Gene Alias: RT1-Ac
• Gene Symbols: RT1-A1
• Host Species: Mouse
• Immunogen: PHA activated rat lymphocytes.
• Purification Method: Protein A
• Quantity: 100 Tests
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 24973
• Target Species: Rat
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG2a

Safety and Handling

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